Effects of Trypanosoma brucei tryptophanyl-tRNA synthetases silencing by RNA interference

The kinetoplast genetic code deviates from the universal code in that 90% of mitochondrial tryptophans are specified by UGA instead of UGG codons. A single nucleus-encoded tRNA Trp(CCA) is used by both nuclear and mitochondria genes, since all kinetoplast tRNAs are imported into the mitochondria fro...

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Bibliographic Details
Main Authors: Liliana Torcoroma García, Ney Ribeiro Leite, Juan D Alfonzo, Otavio Henrique Thiemann
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2007-09-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762007000600016