Generation of contractile actomyosin bundles depends on mechanosensitive actin filament assembly and disassembly

Adhesion and morphogenesis of many non-muscle cells are guided by contractile actomyosin bundles called ventral stress fibers. While it is well established that stress fibers are mechanosensitive structures, physical mechanisms by which they assemble, align, and mature have remained elusive. Here we...

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Bibliographic Details
Main Authors: Sari Tojkander, Gergana Gateva, Amjad Husain, Ramaswamy Krishnan, Pekka Lappalainen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/06126