Low muscle mass in lung cancer is associated with an inflammatory and immunosuppressive tumor microenvironment

Low muscle mass in lung cancer is associated with an inflammatory and immunosuppressive tumor microenvironment

Abstract Background Computed tomographies (CT) are useful for identifying muscle loss in non-small lung cancer (NSCLC) cachectic patients. However, we lack consensus on the best cutoff point for pectoralis muscle loss. We aimed to characterize NSCLC patients based on muscularity, clinical data, and...

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Bibliographic Details
Main Authors: Sarah Santiloni Cury, Diogo de Moraes, Jakeline Santos Oliveira, Paula Paccielli Freire, Patricia Pintor dos Reis, Miguel Luiz Batista, Érica Nishida Hasimoto, Robson Francisco Carvalho
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Journal of Translational Medicine
Subjects:
Non-small cell lung cancer
Machine learning
Computed tomography
Transcriptomics
CD8+ T cells
Online Access:https://doi.org/10.1186/s12967-023-03901-5

Internet

https://doi.org/10.1186/s12967-023-03901-5

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