Proinflammatory and immunoregulatory role of eicosanoids in T cells

Eicosanoids are inflammatory mediators primarily generated by hydrolysis of membrane phospholipids by phospholipase A2 to ω-3 and ω-6 C-20 fatty acids that next are converted to leukotrienes (LTs), prostaglandins (PGs), prostacyclins (PCs) and thromboxanes (TXAs). The rate-limiting and tightly regul...

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Bibliographic Details
Main Authors: Anna Mari Lone, Kjetil eTaskén
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00130/full