Subcellular organization of UBE3A in human cerebral cortex

Subcellular organization of UBE3A in human cerebral cortex

Abstract Background Loss of UBE3A causes Angelman syndrome, whereas excess UBE3A activity appears to increase the risk for autism. Despite this powerful association with neurodevelopmental disorders, there is still much to be learned about UBE3A, including its cellular and subcellular organization i...

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Bibliographic Details
Main Authors: Alain C. Burette, Matthew C. Judson, Alissa N. Li, Edward F. Chang, William W. Seeley, Benjamin D. Philpot, Richard J. Weinberg
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Molecular Autism
Subjects:
Angelman syndrome
E6-AP
Axon terminal
Mitochondria
Euchromatin
Online Access:http://link.springer.com/article/10.1186/s13229-018-0238-0

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http://link.springer.com/article/10.1186/s13229-018-0238-0

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