Freezing Weakens the Barrier Function of Reconstructed Human Epidermis as Evidenced by Raman Spectroscopy and Percutaneous Permeation

Freezing Weakens the Barrier Function of Reconstructed Human Epidermis as Evidenced by Raman Spectroscopy and Percutaneous Permeation

The development and characterization of reconstructed human epidermis (RHE) is an active area of R&D. RHE can replace animal tissues in pharmaceutical, toxicological and cosmetic sciences, yielding scientific and ethical advantages. RHEs remain costly, however, due to consumables and time requir...

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Bibliographic Details
Main Authors: Yuri Dancik, Hichem Kichou, Christophe Eklouh-Molinier, Martin Soucé, Emilie Munnier, Igor Chourpa, Franck Bonnier
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Pharmaceutics
Subjects:
reconstructed human epidermis
EpiSkin™
freezing
storage
Raman spectroscopy
skin barrier
Online Access:https://www.mdpi.com/1999-4923/12/11/1041

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https://www.mdpi.com/1999-4923/12/11/1041

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