Chemical-Mediated Targeted Protein Degradation in Neurodegenerative Diseases
Neurodegenerative diseases, including Alzheimer’s disease, Huntington’s disease, and Parkinson’s disease, are a class of diseases that lead to dysfunction of cognition and mobility. Aggregates of misfolded proteins such as β-amyloid, tau, α-synuclein, and polyglutamates are known to be among the mai...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-06-01
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Series: | Life |
Subjects: | |
Online Access: | https://www.mdpi.com/2075-1729/11/7/607 |