Viral Interference with Functions of the Cellular Receptor Tyrosine Phosphatase CD45

The receptor tyrosine phosphatase CD45 is expressed on the surface of almost all cells of hematopoietic origin. CD45 functions are central to the development of T cells and determine the threshold at which T and B lymphocytes can become activated. Given this pivotal role of CD45 in the immune system...

Full description

Bibliographic Details
Main Authors: Nadine Thiel, Jasmin Zischke, Endrit Elbasani, Penelope Kay-Fedorov, Martin Messerle
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/7/3/1540