Automated Detection of Conformational Epitopes Using Phage Display Peptide Sequences

Background Precise determination of conformational epitopes of neutralizing antibodies represents a key step in the rational design of novel vaccines. A powerful experimental method to gain insights on the physical chemical nature of conformational epitopes is the selection of linear peptides that b...

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Bibliographic Details
Main Authors: Surendra S Negi, Werner Braun
Format: Article
Language:English
Published: SAGE Publishing 2009-01-01
Series:Bioinformatics and Biology Insights
Online Access:https://doi.org/10.4137/BBI.S2745