ALKBH5 promotes hypopharyngeal squamous cell carcinoma apoptosis by targeting TLR2 in a YTHDF1/IGF2BP2-mediated manner

Abstract Hypopharyngeal squamous cell carcinoma (HPSCC) is one of the most aggressive cancers and is notorious for its extremely poor prognosis. However, very few molecular biological studies have been performed. As a novel method of epigenetic gene modulation, N6-methyladenosine (m6A) RNA modificat...

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Bibliographic Details
Main Authors: Jing Ye, Yuting Wu, Yao Chen, Yiyue Ren, Xiaohua Jiang, Zhihuai Dong, Jingna Zhang, Mao Jin, Xiaozhen Chen, Zhanggui Wang, Mang Xiao
Format: Article
Language:English
Published: Nature Publishing Group 2023-08-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01589-6