Vasoactive intestinal polypeptide promotes intestinal barrier homeostasis and protection against colitis in mice.

Inflammatory bowel disease is a chronic gastrointestinal inflammatory disorder associated with changes in neuropeptide expression and function, including vasoactive intestinal peptide (VIP). VIP regulates intestinal vasomotor and secretomotor function and motility; however, VIP's role in develo...

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Bibliographic Details
Main Authors: Xiujuan Wu, Victoria S Conlin, Vijay Morampudi, Natasha R Ryz, Yasmin Nasser, Ganive Bhinder, Kirk S Bergstrom, Hong B Yu, Chris C M Waterhouse, Allison M J Buchan, Oana E Popescu, William T Gibson, James A Waschek, Bruce A Vallance, Kevan Jacobson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4416880?pdf=render