Protective Effect of Antioxidants in Nitric Oxide/COX-2 Interaction during Inflammatory Pain: The Role of Nitration

Protective Effect of Antioxidants in Nitric Oxide/COX-2 Interaction during Inflammatory Pain: The Role of Nitration

In clinical practice, inflammatory pain is an important, unresolved health problem, despite the utilization of non-steroidal anti-inflammatory drugs (NSAIDs). In the last decade, different studies have proven that reactive oxygen species (ROS) and reactive nitrogen species (RNS) are involved in the...

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Bibliographic Details
Main Authors: Sara Ilari, Concetta Dagostino, Valentina Malafoglia, Filomena Lauro, Luigino Antonio Giancotti, Antonella Spila, Stefania Proietti, Domenica Ventrice, Milena Rizzo, Micaela Gliozzi, Ernesto Palma, Fiorella Guadagni, Daniela Salvemini, Vincenzo Mollace, Carolina Muscoli
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Antioxidants
Subjects:
inflammation
cyclooxygenase 2 (COX-2)
prostaglandin E<sub>2</sub> (PGE<sub>2</sub>)
lactate dehydrogenase (LDH)
nitration
malondialdehyde (MDA)
Online Access:https://www.mdpi.com/2076-3921/9/12/1284

Internet

https://www.mdpi.com/2076-3921/9/12/1284

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