Histotype-Dependent Oligodendroglial PrP Pathology in Sporadic CJD: A Frequent Feature of the M2C “Strain”

In sporadic Creutzfeldt-Jakob disease, molecular subtypes are neuropathologically well identified by the lesioning profile and the immunohistochemical PrP<sup>d</sup> deposition pattern in the grey matter (histotypes). While astrocytic PrP pathology has been reported in variant CJD and s...

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Bibliographic Details
Main Authors: Ellen Gelpi, Sigrid Klotz, Nuria Vidal-Robau, Gerda Ricken, Günther Regelsberger, Thomas Ströbel, Ognian Kalev, Marlene Leoni, Herbert Budka, Gabor G. Kovacs
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/13/9/1796