Ribosome inactivation by Escherichia coli GTPase RsgA inhibits T4 phage

Ribosome inactivation by Escherichia coli GTPase RsgA inhibits T4 phage

IntroductionBacteria must combat phages, and myriad bacterial anti-phage systems have been discovered that reduce host metabolism, for example, by depleting energetic compounds like ATP and NAD+. Hence, these systems indirectly inhibit protein production. Surprisingly, direct reduction of ribosome a...

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Bibliographic Details
Main Authors: Laura Fernández-García, María Tomás, Thomas K. Wood
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Microbiology
Subjects:
RsgA
phage inhibition
ribosome inactivation
persistence
ribosomes
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1242163/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2023.1242163/full

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