Upregulation of Vitamin C Transporter Functional Expression in 5xFAD Mouse Intestine

Upregulation of Vitamin C Transporter Functional Expression in 5xFAD Mouse Intestine

The process of obtaining ascorbic acid (AA) via intestinal absorption and blood circulation is carrier-mediated utilizing the AA transporters SVCT1 and SVCT2, which are expressed in the intestine and brain (SVCT2 in abundance). AA concentration is decreased in Alzheimer’s disease (AD), but informati...

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Bibliographic Details
Main Authors: Trevor Teafatiller, Christopher W. Heskett, Anshu Agrawal, Jonathan S. Marchant, Janet E. Baulch, Munjal M. Acharya, Veedamali S. Subramanian
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Nutrients
Subjects:
Vitamin C
transport
Alzheimer’s disease
SVCT1
SVCT2
Online Access:https://www.mdpi.com/2072-6643/13/2/617

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https://www.mdpi.com/2072-6643/13/2/617

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