Bioactive Polyphenols from Pomegranate Juice Reduce 5-Fluorouracil-Induced Intestinal Mucositis in Intestinal Epithelial Cells

Bioactive Polyphenols from Pomegranate Juice Reduce 5-Fluorouracil-Induced Intestinal Mucositis in Intestinal Epithelial Cells

Intestinal epithelial cells (IECs) play a pivotal role in maintaining intestinal homeostasis. Different noxious agents, among them also anticancer therapies, can impair intestinal epithelial integrity triggering inflammation and oxidative stress. A frequent complication of chemotherapy is gastrointe...

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Bibliographic Details
Main Authors: Giacomo Pepe, Shara Francesca Rapa, Emanuela Salviati, Alessia Bertamino, Giulia Auriemma, Stella Cascioferro, Giuseppina Autore, Andrea Quaroni, Pietro Campiglia, Stefania Marzocco
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Antioxidants
Subjects:
intestinal epithelial cells
<i>Punica granatum</i> L.
inflammation
oxidative stress
5-fluorouracil
gastrointestinal mucositis
Online Access:https://www.mdpi.com/2076-3921/9/8/699

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https://www.mdpi.com/2076-3921/9/8/699

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