RNA-sequencing analysis of lung primary fibroblast response to eosinophil-degranulation products predicts downstream effects on inflammation, tissue remodeling and lipid metabolism

RNA-sequencing analysis of lung primary fibroblast response to eosinophil-degranulation products predicts downstream effects on inflammation, tissue remodeling and lipid metabolism

Abstract Background The association of eosinophils with inflammation and tissue remodeling is at least partially due to their release of toxic granule proteins and other mediators, including cytokines. Tissue remodeling and consequent functional defects are affected by activity of connective tissue...

Full description

Bibliographic Details
Main Authors: Stephane Esnault, Ksenija Bernau, Elizabeth E. Torr, Yury A. Bochkov, Nizar N. Jarjour, Nathan Sandbo
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Respiratory Research
Subjects:
Fibroblast
Eosinophil
Il-3
IgG
Degranulation
Lung
Online Access:http://link.springer.com/article/10.1186/s12931-017-0669-8

Internet

http://link.springer.com/article/10.1186/s12931-017-0669-8

Similar Items