BLM and RMI1 alleviate RPA inhibition of TopoIIIα decatenase activity.

RPA is a single-stranded DNA binding protein that physically associates with the BLM complex. RPA stimulates BLM helicase activity as well as the double Holliday junction dissolution activity of the BLM-topoisomerase IIIα complex. We investigated the effect of RPA on the ssDNA decatenase activity of...

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Bibliographic Details
Main Authors: Jay Yang, Csanad Z Bachrati, Ian D Hickson, Grant W Brown
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3401101?pdf=render