A pilot study investigating plasma pharmacokinetics and tolerance of oral capecitabine in carcinoma-bearing dogs

Abstract Background Capecitabine is an oral prodrug of the active metabolite 5-fluorouracil, which has been used effectively in human colorectal, head and neck, and mammary carcinomas. Capecitabine has several properties that make it an attractive treatment option for dogs: (i) it is relatively inex...

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Bibliographic Details
Main Authors: Sarah Wetzel, Janean Fidel, Dale Whittington, Nicolas F. Villarino
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Veterinary Research
Subjects:
Online Access:https://doi.org/10.1186/s12917-023-03805-y