Distinct and redundant functions of cyclin E1 and cyclin E2 in development and cancer

<p>Abstract</p> <p>The highly conserved E-type cyclins are core components of the cell cycle machinery, facilitating the transition into S phase through activation of the cyclin dependent kinases, and assembly of pre-replication complexes on DNA. Cyclin E1 and cyclin E2 are assumed...

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Bibliographic Details
Main Authors: Musgrove Elizabeth A, Caldon C
Format: Article
Language:English
Published: BMC 2010-01-01
Series:Cell Division
Online Access:http://www.celldiv.com/content/5/1/2