Distinct and redundant functions of cyclin E1 and cyclin E2 in development and cancer
<p>Abstract</p> <p>The highly conserved E-type cyclins are core components of the cell cycle machinery, facilitating the transition into S phase through activation of the cyclin dependent kinases, and assembly of pre-replication complexes on DNA. Cyclin E1 and cyclin E2 are assumed...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-01-01
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Series: | Cell Division |
Online Access: | http://www.celldiv.com/content/5/1/2 |