L-Dopa and the albino riddle: content of L-Dopa in the developing retina of pigmented and albino mice.

The absence or deficiency of melanin as in albinos, has detrimental effects on retinal development that include aberrant axonal projections from eye to brain and impaired vision. In pigmented retinal pigment epithelium (RPE), dihydroxyphenalanine (L-Dopa), an intermediate in the synthetic path for m...

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Bibliographic Details
Main Authors: Suzanne Roffler-Tarlov, Jin Hong Liu, Elena N Naumova, Maria Margarita Bernal-Ayala, Carol A Mason
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3602463?pdf=render