Effect of Clarithromycin on the Pharmacokinetics of Cabergoline in Healthy Controls and in Patients With Parkinson’s Disease

Abstract.: Cabergoline is used in the treatment of Parkinson’s disease (PD). Clarithromycin is a potent inhibitor of CYP3A4 and P-glycoprotein and is often co-administered with cabergoline in usual clinical practice. We studied the effect of clarithromycin co-administration on the blood concentratio...

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Bibliographic Details
Main Authors: Akiko Nakatsuka, Masahiro Nagai, Hayato Yabe, Noriko Nishikawa, Takuo Nomura, Hiroyoko Moritoyo, Takashi Moritoyo, Masahiro Nomoto
Format: Article
Language:English
Published: Elsevier 2006-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319345396