The role of bafilomycin as a therapeutic agent in the modulation of endo-lysosomal store of rat hepatocytes

Endo-lysosomal system through the process of autophagy is involved in the pathogenesis of many diseases. Acidification of these organelles is carried out by V-type H+-ATPases, which is inhibited by bafilomycin A1. Endosomes and lysosomes are also important Ca2+-storage in a cell. Nіcotіnіc acіd aden...

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Bibliographic Details
Main Authors: S.V.  Bychkova, A.R. Stasyshyn, M.A. Bychkov
Format: Article
Language:English
Published: Dnipro State Medical University 2022-09-01
Series:Medičnì Perspektivi
Subjects:
Online Access:http://journals.uran.ua/index.php/2307-0404/article/view/265768