The p53-mediated cell cycle regulation is a potential mechanism for emodin-suppressing osteosarcoma cells

Background: As the most common primary bone cancer, the therapy of osteosarcoma requires further study. An anthraquinone derivative, emodin, has been found to have anticancer potential. We proposed that emodin suppresses osteosarcoma by cell cycle regulation mediated by p53. Methods: This study dete...

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Bibliographic Details
Main Authors: Qian Zhang, Shuli Hao, Guangyou Wei, Xiangyu Liu, Yang Miao
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024028810