Characterization and ex vivo Expansion of Human Placenta-Derived Natural Killer Cells for Cancer Immunotherapy

Characterization and ex vivo Expansion of Human Placenta-Derived Natural Killer Cells for Cancer Immunotherapy

Recent clinical studies suggest that adoptive transfer of donor-derived natural killer (NK) cells may improve clinical outcome in hematological malignancies and some solid tumors by direct antitumor effects as well as by reduction of graft versus host disease (GVHD). NK cells have also been shown to...

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Bibliographic Details
Main Authors: Xiaokui eZhang, Lin eKang, Vanessa eVoskinarian-Berse, Eric eLaw, Tiffany eReddin, Mohit eBhatia, Alexandra eHariri, Yuhong eNing, David eDong, Timothy eMaguire, Martin eYarmush, Wolfgang eHofgartner, Stewart eAbbot, Robert eHariri
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-05-01
Series:Frontiers in Immunology
Subjects:
miRNA
placental-derived natural killer cells
ex vivo expansion
anti-tumor cytolytic activity
cellular immunotherapy
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00101/full

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http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00101/full

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