Histone H3 lysine 4 methylation is associated with the transcriptional reprogramming efficiency of somatic nuclei by oocytes

<p>Abstract</p> <p>Background</p> <p>When the nuclei of mammalian somatic cells are transplanted to amphibian oocytes in the first meiotic prophase, they are rapidly induced to begin transcribing several pluripotency genes, including Sox2 and Oct4. The more differentiat...

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Bibliographic Details
Main Authors: Murata Kazutaka, Kouzarides Tony, Bannister Andrew J, Gurdon John B
Format: Article
Language:English
Published: BMC 2010-02-01
Series:Epigenetics & Chromatin
Online Access:http://www.epigeneticsandchromatin.com/content/3/1/4