Transgenic Rabbits Expressing Ovine PrP Are Susceptible to Scrapie.

Transgenic Rabbits Expressing Ovine PrP Are Susceptible to Scrapie.

Transmissible spongiform encephalopathies (TSEs) are a group of neurodegenerative diseases affecting a wide range of mammalian species. They are caused by prions, a proteinaceous pathogen essentially composed of PrPSc, an abnormal isoform of the host encoded cellular prion protein PrPC. Constrained...

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Bibliographic Details
Main Authors: Pierre Sarradin, Céline Viglietta, Claude Limouzin, Olivier Andréoletti, Nathalie Daniel-Carlier, Céline Barc, Mathieu Leroux-Coyau, Patricia Berthon, Jérôme Chapuis, Christelle Rossignol, Jean-Luc Gatti, Maya Belghazi, Valérie Labas, Jean-Luc Vilotte, Vincent Béringue, Frédéric Lantier, Hubert Laude, Louis-Marie Houdebine
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005077

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https://doi.org/10.1371/journal.ppat.1005077

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