Development of a sequencing system for spatial decoding of DNA barcode molecules at single-molecule resolution

Oguchi et al. developed an in-house sequencing system to spatially decode DNA barcode molecules at single-molecule resolution. They obtain an average read length of 20 nucleotides with an error rate of less than 5% per nucleotide. Leveraging this system, they devised a molecular foot printing method...

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Bibliographic Details
Main Authors: Yusuke Oguchi, Hirofumi Shintaku, Sotaro Uemura
Format: Article
Language:English
Published: Nature Portfolio 2020-12-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-020-01499-8