Synchrony of biomarker variability indicates a critical transition: Application to mortality prediction in hemodialysis

Synchrony of biomarker variability indicates a critical transition: Application to mortality prediction in hemodialysis

Summary: Critical transition theory suggests that complex systems should experience increased temporal variability just before abrupt state changes. We tested this hypothesis in 763 patients on long-term hemodialysis, using 11 biomarkers collected every two weeks and all-cause mortality as a proxy f...

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Bibliographic Details
Main Authors: Alan A. Cohen, Diana L. Leung, Véronique Legault, Dominique Gravel, F. Guillaume Blanchet, Anne-Marie Côté, Tamàs Fülöp, Juhong Lee, Frédérik Dufour, Mingxin Liu, Yuichi Nakazato
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:iScience
Subjects:
health sciences
medicine
health informatics
biological sciences
bioinformatics
computational bioinformatics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222006563

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http://www.sciencedirect.com/science/article/pii/S2589004222006563

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