Defining cardiac fibrosis complexity and regulation towards therapeutic development

Abstract Cardiac fibrosis is insidious, accelerating cardiovascular diseases, heart failure, and death. With a notable lack of effective therapies, advances in both understanding and targeted treatment of fibrosis are urgently needed. Remodelling of the extracellular matrix alters the biomechanical...

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Bibliographic Details
Main Authors: Bethany Claridge, Auriane Drack, Alexander R. Pinto, David W. Greening
Format: Article
Language:English
Published: Wiley 2023-02-01
Series:Clinical and Translational Discovery
Subjects:
Online Access:https://doi.org/10.1002/ctd2.163