Differentiation-dependent interpentameric disulfide bond stabilizes native human papillomavirus type 16.

Differentiation-dependent interpentameric disulfide bond stabilizes native human papillomavirus type 16.

Genetic and biochemical analyses of human papillomavirus type 16 (HPV16) capsids have shown that certain conserved L1 cysteine residues are critical for capsid assembly, integrity, and maturation. Since previous studies utilized HPV capsids produced in monolayer culture-based protein expression syst...

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Bibliographic Details
Main Authors: Michael J Conway, Linda Cruz, Samina Alam, Neil D Christensen, Craig Meyers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3139651?pdf=render

Internet

http://europepmc.org/articles/PMC3139651?pdf=render

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