BRIDGING THE IMMUNOGENICITY OF A TETRAVALENT DENGUE VACCINE CANDIDATE (TAK-003) FROM CHILDREN AND ADOLESCENTS TO ADULTS

Intro: Dengue efficacy studies are not feasible in dengue non-endemic countries. For TAK-003, we present an immunobridging analysis to infer vaccine efficacy as determined in the DEN-301 phase 3 efficacy trial conducted in children and adolescents from eight dengue-endemic countries to adults from n...

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Bibliographic Details
Main Authors: C. Halim, V. Tricou, F. Nordio, N. Folschweiller
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:International Journal of Infectious Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971223001571