Distinct leukocyte populations and cytokine secretion profiles define tumoral and peritumoral areas in renal cell carcinoma

Distinct leukocyte populations and cytokine secretion profiles define tumoral and peritumoral areas in renal cell carcinoma

Renal cell carcinoma (RCC) is a common malignancy frequently diagnosed at the metastatic stage. We performed a comprehensive analysis of the tumor immune microenvironment (TIME) in RCC patients, including the peritumoral tissue microenvironment, to characterize the phenotypic patterns and functional...

Full description

Bibliographic Details
Main Authors: Martina Borcinova, Robin Bartolini, Lily Koumbas Foley, Vojtech Novak, Pavla Taborska, Dmitry Stakheev, Michal Rataj, Daniel Smrz, Martina Fialova, Jaromir Hacek, Martin Komarc, Stepan Vesely, Marek Babjuk, Ilja Striz, Jirina Bartunkova, Tomas Buchler, Zuzana Ozaniak Strizova
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Translational Oncology
Subjects:
Kidney cancer
Tumor-infiltrating lymphocytes
Tumor immune microenvironment
Renal carcinoma immunotherapy
RCC TME
CAFs
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523324000172

Internet

http://www.sciencedirect.com/science/article/pii/S1936523324000172

Similar Items