Regulation of chromatin architecture by transcription factor binding

Transcription factors (TF) bind to chromatin and regulate the expression of genes. The pair Myc:Max binds to E-box regulatory DNA elements throughout the genome to control the transcription of a large group of specific genes. We introduce an implicit modeling protocol for Myc:Max binding to mesoscal...

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Bibliographic Details
Main Authors: Stephanie Portillo-Ledesma, Suckwoo Chung, Jill Hoffman, Tamar Schlick
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-01-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/91320