Mechanisms by Which 17β-Estradiol (E2) Suppress Neuronal cox-2 Gene Expression.

E2 attenuates inflammatory responses by suppressing expression of pro-inflammatory genes. Given that inflammation is increasingly being associated with neurodegenerative and psychiatric processes, we sought to elucidate mechanisms by which E2 down-regulates a component of an inflammatory response, c...

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Bibliographic Details
Main Authors: Winfred Stacey, Shreyas Bhave, Rosalie M Uht
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5010190?pdf=render