Dental pain report in children and genetic polymorphism (rs4818) in Catechol-O-Methyltransferase (COMT) gene: a cross- sectional study

Dental pain report in children and genetic polymorphism (rs4818) in Catechol-O-Methyltransferase (COMT) gene: a cross- sectional study

Abstract Aim: Polymorphisms in the COMT gene can alter enzymatic functions, raising levels of endogenous catecholamines, which stimulates beta-adrenergic receptors related to pain. This study aimed to evaluate whether a polymorphism in the COMT gene (rs4818) is associated with dental pain in childr...

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Bibliographic Details
Main Authors: Bruna Leticia Vessoni Menoncin, Aluhê Lopes Fatturi, Rafaela Scariot, José Vitor Nogara Borges Menezes, João Armando Brancher, Juliana Feltrin-Souza
Format: Article
Language:English
Published: University of São Paulo 2024-01-01
Series:Journal of Applied Oral Science
Subjects:
Genetic polymorphism
Pain perception
Toothache
Child
Pediatric dentistry
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572024000100401&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572024000100401&tlng=en

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