Multigene Mutation Profiling and Clinical Characteristics of Small-Cell Lung Cancer in Never-Smokers vs. Heavy Smokers (Geno1.3-CLICaP)

Multigene Mutation Profiling and Clinical Characteristics of Small-Cell Lung Cancer in Never-Smokers vs. Heavy Smokers (Geno1.3-CLICaP)

Objectives: Lung cancer is a heterogeneous disease. Presentation and prognosis are known to vary according to several factors, such as genetic and demographic characteristics. Small-cell lung cancer incidence is increasing in never-smokers. However, the disease phenotype in this population is differ...

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Main Authors: Andrés F. Cardona, Leonardo Rojas, Zyanya Lucia Zatarain-Barrón, Alejandro Ruiz-Patiño, Luisa Ricaurte, Luis Corrales, Claudio Martín, Helano Freitas, Vladmir Cláudio Cordeiro de Lima, July Rodriguez, Jenny Avila, Melissa Bravo, Pilar Archila, Hernán Carranza, Carlos Vargas, Jorge Otero, Feliciano Barrón, Niki Karachaliou, Rafael Rosell, Oscar Arrieta
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Oncology
Subjects:
small-cell lung cancer
genome profile
next-generation sequencing
cancer in never-smokers
TP53
RB1
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00254/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.00254/full

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