Vascular endothelial growth factor improves the therapeutic effects of cyclodextrin in Niemann-Pick type C mice

Niemann-Pick type C disease (NP-C) is a fatal neurodegenerative disorder caused by a deficiency in the function of the NPC1 gene. Malfunction of this gene/protein leads to progressive accumulation of unesterified cholesterol and sphingolipids in many organs, including the brain. To date, drugs that...

Full description

Bibliographic Details
Main Authors: Min Seock Jeong, Jae-sung Bae, Hee Kyung Jin
Format: Article
Language:English
Published: Taylor & Francis Group 2019-09-01
Series:Animal Cells and Systems
Subjects:
Online Access:http://dx.doi.org/10.1080/19768354.2019.1651768