Vascular endothelial growth factor improves the therapeutic effects of cyclodextrin in Niemann-Pick type C mice
Niemann-Pick type C disease (NP-C) is a fatal neurodegenerative disorder caused by a deficiency in the function of the NPC1 gene. Malfunction of this gene/protein leads to progressive accumulation of unesterified cholesterol and sphingolipids in many organs, including the brain. To date, drugs that...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2019-09-01
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Series: | Animal Cells and Systems |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/19768354.2019.1651768 |