Vaccine Strain-Specificity of Protective HLA-Restricted Class 1 P. falciparum Epitopes.

Vaccine Strain-Specificity of Protective HLA-Restricted Class 1 P. falciparum Epitopes.

A DNA prime/adenovirus boost malaria vaccine encoding Plasmodium falciparum strain 3D7 CSP and AMA1 elicited sterile clinical protection associated with CD8+ T cell interferon-gamma (IFN-γ) cells responses directed to HLA class 1-restricted AMA1 epitopes of the vaccine strain 3D7. Since a highly eff...

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Bibliographic Details
Main Authors: Martha Sedegah, Bjoern Peters, Michael R Hollingdale, Harini D Ganeshan, Jun Huang, Fouzia Farooq, Maria N Belmonte, Arnel D Belmonte, Keith J Limbach, Carter Diggs, Lorraine Soisson, Ilin Chuang, Eileen D Villasante
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5047630?pdf=render

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http://europepmc.org/articles/PMC5047630?pdf=render

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