Construction and immunogenicity of SARS-CoV-2 virus-like particle expressed by recombinant baculovirus BacMam

Construction and immunogenicity of SARS-CoV-2 virus-like particle expressed by recombinant baculovirus BacMam

ABSTRACT The pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to evolve to give rise to variants of concern that can escape vaccine-induced immunity. As such, more effective vaccines are urgently needed. In this study, we evaluated virus-like particle (VLP) as a vaccin...

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Bibliographic Details
Main Authors: Hai Trong Nguyen, Darryl Falzarano, Volker Gerdts, Qiang Liu
Format: Article
Language:English
Published: American Society for Microbiology 2024-08-01
Series:Microbiology Spectrum
Subjects:
SARS-CoV-2
virus-like particle
baculovirus BacMam
vaccine
immune response
pseudotyped lentivirus
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00959-24

Internet

https://journals.asm.org/doi/10.1128/spectrum.00959-24

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