Vector Aided Microenvironment programming (VAMP): reprogramming the TME with MVA virus expressing IL-12 for effective antitumor activity

Background Tumor microenvironment (TME) represents a critical hurdle in cancer immunotherapy, given its ability to suppress antitumor immunity. Several efforts are made to overcome this hostile TME with the development of new therapeutic strategies modifying TME to boost antitumor immunity. Among th...

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Bibliographic Details
Main Authors: Fulvia Troise, Anna Morena D'Alise, Guido Leoni, Maria De Lucia, Linda Nocchi, Elisa Micarelli, Gabriella Cotugno, Irene Garzia, Elisa Scarselli, Laura Seclì, Luigia Infante, Lidia Avalle, Giulia Sdruscia, Simona Allocca, Giuseppina Romano
Format: Article
Language:English
Published: BMJ Publishing Group 2023-04-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/11/4/e006718.full