On the quasi-steady-state approximation in an open Michaelis–Menten reaction mechanism

On the quasi-steady-state approximation in an open Michaelis–Menten reaction mechanism

The conditions for the validity of the standard quasi-steady-state approximation in the Michaelis–Menten mechanism in a closed reaction vessel have been well studied, but much less so the conditions for the validity of this approximation for the system with substrate inflow. We analyze quasi-steady-...

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Bibliographic Details
Main Authors: Justin Eilertsen, Marc R. Roussel, Santiago Schnell, Sebastian Walcher
Format: Article
Language:English
Published: AIMS Press 2021-04-01
Series:AIMS Mathematics
Subjects:
singular perturbation
slow manifold
quasi-steady state
michaelis–menten mechanism
critical manifold
gronwall lemma
poincaré sphere
Online Access:http://www.aimspress.com/article/doi/10.3934/math.2021398?viewType=HTML

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http://www.aimspress.com/article/doi/10.3934/math.2021398?viewType=HTML

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