A Broad-Spectrum Infection Diagnostic that Detects Pathogen-Associated Molecular Patterns (PAMPs) in Whole Blood

A Broad-Spectrum Infection Diagnostic that Detects Pathogen-Associated Molecular Patterns (PAMPs) in Whole Blood

Background: Blood cultures, and molecular diagnostic tests that directly detect pathogen DNA in blood, fail to detect bloodstream infections in most infected patients. Thus, there is a need for a rapid test that can diagnose the presence of infection to triage patients, guide therapy, and decrease t...

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Bibliographic Details
Main Authors: Mark Cartwright, Martin Rottman, Nathan I. Shapiro, Benjamin Seiler, Patrick Lombardo, Nazita Gamini, Julie Tomolonis, Alexander L. Watters, Anna Waterhouse, Dan Leslie, Dana Bolgen, Amanda Graveline, Joo H. Kang, Tohid Didar, Nikolaos Dimitrakakis, David Cartwright, Michael Super, Donald E. Ingber
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:EBioMedicine
Subjects:
Biomarker
Mannose binding lectin
Infection diagnostic
Sepsis
Blood culture
C-reactive protein
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396416302584

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http://www.sciencedirect.com/science/article/pii/S2352396416302584

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