Nr4a1 marks a distinctive ILC2 activation subset in the mouse inflammatory lung

Nr4a1 marks a distinctive ILC2 activation subset in the mouse inflammatory lung

Abstract Background Group 2 innate lymphoid cells (ILC2s) are critical sources of type 2 cytokines and represent one of the major tissue-resident lymphoid cells in the mouse lung. However, the molecular mechanisms underlying ILC2 activation under challenges are not fully understood. Results Here, us...

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Bibliographic Details
Main Authors: Shasha Xu, Yu Zhang, Xingjie Liu, Huisheng Liu, Xinya Zou, Linlin Zhang, Jing Wang, Zhiwei Zhang, Xiang Xu, Mingxia Li, Kairui Li, Shuyue Shi, Ying Zhang, Zhichao Miao, Jie Zha, Yong Yu
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Biology
Subjects:
ILC2 subset
ILC2 activation
Nr4a1
PD-1
scRNA-seq
Online Access:https://doi.org/10.1186/s12915-023-01690-3

Internet

https://doi.org/10.1186/s12915-023-01690-3

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