Non-Toxic and Ultra-Small Biosilver Nanoclusters Trigger Apoptotic Cell Death in Fluconazole-Resistant <i>Candida albicans</i> via Ras Signaling

Non-Toxic and Ultra-Small Biosilver Nanoclusters Trigger Apoptotic Cell Death in Fluconazole-Resistant <i>Candida albicans</i> via Ras Signaling

Silver-based nanostructures are suitable for many biomedical applications, but to be useful therapeutic agents, the high toxicity of these nanomaterials must be eliminated. Here, we biosynthesize nontoxic and ultra-small silver nanoclusters (rsAg@NCs) using metabolites of usnioid lichen (a symbiotic...

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Bibliographic Details
Main Authors: Prateeksha, Braj Raj Singh, Vijai Kumar Gupta, Farah Deeba, Rajesh Bajpai, Vivek Pandey, Alim H. Naqvi, Dalip Kumar Upreti, Nicholas Gathergood, Yueming Jiang, Hesham A. El Enshasy, Essam Nageh Sholkamy, Ashraf A. Mostafa, Abd El-Latif Hesham, Brahma N. Singh
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Biomolecules
Subjects:
fluconazole-resistant <i>Candida albicans</i>
biosilver nanoclusters
apoptosis
Ras signaling pathway
oxidative stress
proteomics
Online Access:https://www.mdpi.com/2218-273X/9/2/47

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https://www.mdpi.com/2218-273X/9/2/47

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