Promoter-enhancer looping and shadow enhancers of the mouse αA-crystallin locus
Gene regulation by enhancers is important for precise temporal and spatial gene expression. Enhancers can drive gene expression regardless of their location, orientation or distance from the promoter. Changes in chromatin conformation and chromatin looping occur to bring the promoter and enhancers i...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2018-12-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/7/12/bio036897 |