Activation of WNT7b autocrine eases metastasis of colorectal cancer via epithelial to mesenchymal transition and predicts poor prognosis

Activation of WNT7b autocrine eases metastasis of colorectal cancer via epithelial to mesenchymal transition and predicts poor prognosis

Abstract Background Aberrant activation of the Wnt/β-catenin signaling pathway is one of the most frequent abnormalities in human cancer, including colorectal cancer (CRC). Previous studies revealed pivotal functions of WNT family members in colorectal cancer, as well as their prognostic values. Nev...

Description complète

Détails bibliographiques
Auteurs principaux: Shuai Jiang, Qiwen Li, Yimin Liu, Huimin Zhang, Qianyu Wang, Yu Chen, Xiaoyang Shi, Jun Li, Hailing Zhang, Yi Zhang, Dongqing Xia, Man Wu, Jiajia Lin, Chenglin Zhang, Suhua Pang, Jiamin Jiang, Yan Wen, Peipei Zhang
Format: Article
Langue:English
Publié: BMC 2021-02-01
Collection:BMC Cancer
Sujets:
WNT7b
Wnt/β-catenin signaling pathway
Colorectal cancer (CRC)
Metastasis
Accès en ligne:https://doi.org/10.1186/s12885-021-07898-2

Internet

https://doi.org/10.1186/s12885-021-07898-2

Documents similaires