Combinations of immuno-checkpoint inhibitors predictive biomarkers only marginally improve their individual accuracy

Combinations of immuno-checkpoint inhibitors predictive biomarkers only marginally improve their individual accuracy

Abstract Background There are no accepted universal biomarkers capable to accurately predict response to immuno-checkpoint inhibitors (ICI). Although recent literature has been flooded with studies on ICI predictive biomarkers, available data show that currently approved companion diagnostics either...

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Bibliographic Details
Main Authors: Matteo Pallocca, Davide Angeli, Fabio Palombo, Francesca Sperati, Michele Milella, Frauke Goeman, Francesca De Nicola, Maurizio Fanciulli, Paola Nisticò, Concetta Quintarelli, Gennaro Ciliberto
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Journal of Translational Medicine
Subjects:
Immuno-checkpoint inhibitors biomarkers
Genomics
Immunotherapy
ImmunoPhenoScore
TIDE
RNA-seq
Online Access:http://link.springer.com/article/10.1186/s12967-019-1865-8

Internet

http://link.springer.com/article/10.1186/s12967-019-1865-8

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