Matrix metalloproteinases as biomarkers and therapeutic targets in colitis-associated cancer

Matrix metalloproteinases as biomarkers and therapeutic targets in colitis-associated cancer

Colorectal cancer (CRC) remains a major cause of morbidity and mortality. Therapeutic approaches for advanced CRC are limited and rarely provide long-term benefit. Enzymes comprising the 24-member matrix metalloproteinase (MMP) family of zinc- and calcium-dependent endopeptidases are key players in...

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Bibliographic Details
Main Authors: Natalia Sampaio Moura, Alyssa Schledwitz, Madeline Alizadeh, Seema A. Patil, Jean-Pierre Raufman
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Oncology
Subjects:
matrix metalloproteinases
colitis-associated cancer
colorectal cancer
inflammatory bowel disease
tissue inhibitors of metalloproteinases
enzymes
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1325095/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1325095/full

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