Leukocyte CD11b expression is not essential for the development of atherosclerosis in mice

Leukocyte CD11b expression is not essential for the development of atherosclerosis in mice

CD11b is an α chain of the leukocyte β2-integrin, Mac-1, which mediates binding and extravasation of leukocytes. Because this event is critical in atherosclerosis, we examined the role of CD11b in lesion formation. Atherosclerosis-susceptible, low density lipoprotein receptor-deficient (LDL-R−/−) mi...

Full description

Bibliographic Details
Main Authors: Nobuhiko Kubo, William A. Boisvert, Christie M. Ballantyne, Linda K. Curtiss
Format: Article
Language:English
Published: Elsevier 2000-07-01
Series:Journal of Lipid Research
Subjects:
transgenic/knockout
fluorescence-activated cell sorting
in vivo animal models
adhesion molecules
inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520320101

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520320101

Similar Items